The Lightbed Photodynamic Therapy (PDT) Cancer Treatment Trial

Monitoring treatment effect of photo-dynamic therapy using a lightbed (Light-bed-PDT) in cancer patients by Circulating Tumour Cell (CTC) analysis

Background
Prevalence of cancer diagnosis is high and attributable to 30% of all deaths in Australia. There is a need for better treatment combined with reliable assessments of treatment effectiveness. This pilot intervention study aims to assess the treatment effectiveness and safety of Light-bed-PDT for patients with cancer using Circulating Tumour Cell (CTC) specimen analyses.

What is Photodynamic Therapy (PDT)
PDT consists of two steps, the oral administration of a chlorophyll-based algal-derived food-grade liquid photosensitiser (Step 1), followed by LED light therapy the next day (Step 2). The photosensitiser has been shown to concentrate in cancer cells, and is activated by light from Light Emitting Diodes (LED) inducing cancer cell death, while also stimulating the immune system.

SEEKING ADULTS DIAGNOSED WITH ANY TYPE OF CANCER

What will I be asked to do?

  1. There will be 5 visits to NIIM on 4 days within 1-2 weeks.
  2. The first and the last visit will take about 15-30 min and will involve a blood test and questionnaires.
  3. There will be 3 treatment sessions, 2x 30 min sessions am and pm on day 1, and one 45 min session 4-5 days later. Participants need to consider one full day and half day for treatment.

Photodynamic Therapy (PDT) with Light-bed
Session 1:
Step 1: Wed: oral administration of photosensitiser taken 15-20 hours before LED light therapy. & Collection of bloods for CTC test 1 week prior.
Step 2: Thu (am): 1x Light-bed therapy for 30 minutes

Session 2:
Step 1 repeat
: Thu (pm): oral administration of photosensitiser as above
Step 2 repeat: Fri (am): 1x Light-bed therapy for 30 minutes

Visit 4 (1 week after lightbed):
30 min CTC Blood test & questionnaires

For more information:

Expressions of interest, please complete the form below,

or email directly to: pdt@niim.com.au Subject heading: lightbed

 

Light-bed Photodynamic Therapy Enquiries

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